Cancer biomarkers

The Cancer Registry has several current projects focusing on cancer biomarkers. The goal of these projects is to identify, develop and validate biological markers that can be used for early detection and increase knowledge about the mechanisms behind cancer development.
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Research projects

Sequencing HPV for biomarker discovery

HPVseq is an cross-institutional research group with three the main goals, To discover HPV biomarkers, delineate HPV evolution and develop HPV detection and characterization methods.

The microbiome as a colorectal cancer screening biomarker

Presence of certain bacteria in the gut are strongly associated with colorectal cancer. This project is a sub-study within the Bowel Cancer Screening in Norway (BCSN) trial that aims to discover gut microbiota biomarkers for colorectal cancer screening.

JanusRNA - Identification of early cancer biomarkers

RNA are involved in numerous cellular processes in cancer development. We are currently investigating RNA as early detection and potential screening biomarkers of cancer.

The impact of obesity and circulating small RNA in the development of endometrial cancer

The project will investigate how age and lifestyle factors affect the expression of circulating small RNA`s among patients with uterine cancer who have submitted samples to the Janus Serum Bank.

Testicular cancer and heredity

Testicular cancer is the most frequent form of cancer among young men, and much indicates that the foundation for the disease is laid already in fetal life. In this Norwegian-Swedish collaborative project, genes that may be important for the development of testicular cancer will be investigated.

miPROC - biomarkers for early detection of ovarian cancer

This study will provide validation of a panel of microRNAs for ovarian cancer early detection and direction of women with suspicion of cancer to specialist care.

EULAT eradicate GBC

EULAT Eradicate Gallbladder Cancer (GBC) aims to improve the prevention, early detection and treatment of gallbladder cancer. The Cancer Registry of Norway is responsible for work package (WP) 3: Novel biomarkers for GBC risk prediction and early detection.

Per- and Polyfluoroalkyl Substances (PFAS)

The project will use samples from the population-based Janus Serum Bank as a "time machine" to explore the relationship between kidney and testicular cancer and exposure to "Eternal Chemicals" Per- and Polyfluoroalkyl Substances (PFAS).