Background and study aims:
In a large number of epidemiologic studies, the relationship between physical activity and cancer risk has been investigated. However, evidence of a beneficial effect in men is poor. Measured cardiorespiratory fitness (CRF) can provide knowledge about the cancer‐preventive value of physical activity. By combinding data from the Oslo Ischemia study and the Cancer Registry, this study aims to investigate the association between phycical activity, fitness and cancer risk and cancer mortality.
The Oslo Ischemia Study is a comprehensive health survey established in 1972, aimed to examine the prevalence and development of coronary heart disease and other cardiovascular diseases in a healthy male population. In total 2014 apparently healthy men participated in the study. CRF was assessed by an incremental bicycle exercise test. Measurements of height, weight, lung capacity, and a panel of blood tests were done and information on lifestyle factors such as smoking habits and physical activity were collected These data were linked to the Norwegian Cancer Registry.
Robsahm TE, Falk RS, Heir T, Sandvik L, Vos L, Erikssen J, Tretli S (2017). Cardiorespiratory fitness and risk of site-specific cancers: a long-term prospective cohort study. Cancer Med, 6 (4), 865-873. PubMed 28317282
Heir T, Falk RS, Robsahm TE, Sandvik L, Erikssen J, Tretli S (2016). Cholesterol and prostate cancer risk: a long-term prospective cohort study. BMC Cancer, 16, 643 PubMed 27535659
Robsahm TE, Falk RS, Heir T, Sandvik L, Vos L, Erikssen JE, Tretli S (2016). Measured cardiorespiratory fitness and self-reported physical activity: associations with cancer risk and death in a long-term prospective cohort study. Cancer Med, 5 (8), 2136-44. PubMed 27227704
Ragnhild Sørum Falk - Oslo University Hospital
Trond Heir - University of Oslo
Leiv Sandvik - Oslo University Hospital
Jan E Erikssen - Oslo University Hospital.