This study will provide validation of a panel of microRNAs for ovarian cancer early detection and direction of women with suspicion of cancer to specialist care.
The project will investigate how age and lifestyle factors affect the expression of circulating small RNA among patients with endometrial cancer who have submitted samples to the Janus serum bank.
Funded by Horizon2020
EULAT Eliminate Gallbladder Cancer (GBC) aims to improve the prevention, early detection and treatment of gallbladder cancer. The Cancer Registry of Norway is responsible for work package (WP) 3: New biomarkers for early detection of GBC.
Testicular cancer is the most frequent form of cancer among young men. The cause of the disease is largely unknown, but hereditary factors and conditions during pregnancy are important. Insight into gene activity in testicular cancer can provide better biomarkers and more precise diagnostics.
Master Thesis by Tharmira Santhirakumar (2023).
miRNAs are small non-coding RNAs that are involved in many cellular processes in cancer development. Studying circulating miRNAs can increase understanding of carcinogenesis. The main purpose of the study is to investigate whether miRNA can be used as a biomarker to diagnose cancer at an early stage.
We have demonstrated that miRNAs can be successfully isolated from the Janus serum samples, with funding from the BIOBANK programme. Biocomputational analyses based on combined data from miRNA sequencing, detailed cancer registry data and environmental exposure data from health surveys, will generate new knowledge in cancer research.
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