Holme is leading the Bowel Cancer Screening department. He manages and coordinates the Norwegian Cancer Registry's work in connection with the introduction of a national program for bowel screening, scheduled to be introduced in 2019. Holme is interested in research concerning bowel screening and quality improvement projects within screening and gastrointestinal endoscopy. He is also leader of the screening pilot: Bowel cancer screening in Norway, at Østfold Hospital Trust and Vestre Viken Hospital Trust.
The ongoing pilot - Bowel cancer screening in Norway. Colonoscopy or fecal occult blood test to screen for bowel cancer: A comparative effectiveness study in the Norwegian bowel screening program. Selected publications: CRISTIN: https://app.cristin.no/persons/show.jsf?id=2295