Trude Eid Robsahm is heading the section for Etiology, within the Research Department. She has a particular interest in the role of modifiable lifestyle factors, in primary and secondary cancer prevention. She is the Cancer Registry's expert on skin cancer, with a particular focus on melanoma. Although UV radiation is the main environmental risk exposure, also other factors are in focus in her research. On the other hand, UV radiation is our main vitamin D source, and in a number of prognostic studies she has investigated the potential beneficial role of vitamin D in cancer development. Moreover, her studies also focus on mechanisms of physical activity in primary and secondary cancer prevention.
Background
She has a master degree in sports science/physiology from NTNU (1993) and has been employed at the Cancer Registry since 1995. She holds a PhD from the Faculty of Medicine, University of Oslo (2004), with the thesis entitled “The influence of etiological factors in sensitive periods of life on cutaneous malignant melanoma, breast-, colon- and prostate cancer: an epidemiologic study focusing mainly on residential history in Norway”. Thereafter, she has held a position as researcher in the Research department.
She also teaches in register-based research and cancer epidemiology at colleges and universities in the Oslo area, she is supervising and has supervised several PhD-students and postdoctoral fellows, and is board member in several academic councils and evaluation committees.
Projects
Obesity, vitamin D, leptin and cutaneous melanoma
Stenehjem JS, Grimsrud TK, Rees JR, Vos L, Babigumira R, Veierød MB, Robsahm TE. A protocol for prospective studies of 25-hydroxyvitamin D, leptin and body mass index in relation to cutaneous melanoma incidence and survival. BMJ Open. 2017 Jun 21;7(6):e014829. doi: 10.1136/bmjopen-2016-014829.
Stenehjem JS, Veierød MB, Nilsen LT, Ghiasvand R, Johnsen B, Grimsrud TK, Babigumira R, Rees JR, Robsahm TE. Anthropometric factors and cutaneous melanoma: Prospective data from the population-based Janus Cohort. Int J Cancer. 2018 Feb 15;142(4):681-690. doi: 10.1002/ijc.31086. Epub 2017 Oct 17.
Gislefoss RE, Stenehjem JS, Hektoen HH, Andreassen BK, Langseth H, Axcrona K, Weiderpass E, Mondul A, Robsahm TE. Vitamin D, obesity and leptin in relation to bladder cancer incidence and survival: prospective protocol study. BMJ Open. 2018 Mar 30;8(3):e019309. doi: 10.1136/bmjopen-2017-019309.
Stenehjem JS, Veierød MB, Nilsen LT, Ghiasvand R, Johnsen B, Grimsrud TK, Babigumira R, Støer NC, Rees JR, Robsahm TE. Anthropometric factors and Breslow thickness: prospective data on 2570 cases of cutaneous melanoma in the population-based Janus Cohort. Br J Dermatol. 2018 Sep;179(3):632-641. doi: 10.1111/bjd.16825. Epub 2018 Jul 26.
Stenehjem JS, Støer NC, Ghiasvand R, Grimsrud TK, Babigumira R, Rees JR, Nilsen LT, Johnsen B, Thorsby PM, Veierød MB, Robsahm TE. Prediagnostic serum 25-hydroxyvitamin D and melanoma risk. Sci Rep. 2020 Nov 18;10(1):20129. doi: 10.1038/s41598-020-77155-2. PMID: 33208828; PMCID: PMC7676247.
Physical activity and cancer
Robsahm TE, Falk RS, Heir T, Sandvik L, Vos L, Erikssen JE, Tretli S. Measured cardiorespiratory fitness and self-reported physical activity: associations with cancer risk and death in a long-term prospective cohort study. Cancer Med. 2016 Aug;5(8):2136-44. doi: 10.1002/cam4.773.
Heir T, Falk RS, Robsahm TE, Sandvik L, Erikssen J, Tretli S. Cholesterol and prostate cancer risk: a long-term prospective cohort study. BMC Cancer. 2016 Aug 17;16:643. doi: 10.1186/s12885-016-2691-5.
Robsahm TE, Falk RS, Heir T, Sandvik L, Vos L, Erikssen J, Tretli S. Cardiorespiratory fitness and risk of site-specific cancers: a long-term prospective cohort study. Cancer Med. 2017 Apr;6(4):865-873. doi: 10.1002/cam4.1043.
Robsahm TE, Heir T, Sandvik L, Prestgaard E, Tretli S, Erikssen JE, Falk RS. Changes in midlife fitness, body mass index, and smoking influence cancer incidence and mortality: A prospective cohort study in men. Cancer Med. 2019 Aug;8(10):4875-4882. doi: 10.1002/cam4.2383.
Falk RS, Heir T, Robsahm TE, Tretli S, Sandvik L, Erikssen JE, Paulsen JE. Fasting Serum Levels of Potassium and Sodium in Relation to Long-Term Risk of Cancer in Healthy Men. Clin Epidemiol. 2020 Jan 9;12:1-8. doi: 10.2147/CLEP.S216438.
Use of prescribed drugs and melanoma risk
Berge LAM, Andreassen BK, Stenehjem JS, Larsen IK, Furu K, Juzeniene A, Roscher I, Heir T, Green A, Veierød MB, Robsahm TE. Cardiovascular, antidepressant and immunosuppressive drug use in relation to risk of cutaneous melanoma: a protocol for a prospective case-control study. BMJ Open. 2019 Feb 20;9(2):e025246. doi: 10.1136/bmjopen-2018-025246.
Berge LAM, Andreassen BK, Stenehjem JS, Heir T, Furu K, Juzeniene A, Roscher I, Larsen IK, Green AC, Veierød MB, Robsahm TE. Use of Antidepressants and Risk of Cutaneous Melanoma: A Prospective Registry-Based Case-Control Study. Clin Epidemiol. 2020 Feb 21;12:193-202. doi: 10.2147/CLEP.S241249.
Berge LAM, Andreassen BK, Stenehjem JS, Heir T, Karlstad Ø, Juzeniene A, Ghiasvand R, Larsen IK, Green AC, Veierød MB, Robsahm TE. Use of Immunomodulating Drugs and Risk of Cutaneous Melanoma: A Nationwide Nested Case-Control Study. Clin Epidemiol. 2020 Dec 18;12:1389-1401. doi: 10.2147/CLEP.S269446. PMID: 33376408; PMCID: PMC7755337.
Betablockers; a novel class of drug targets to block melanoma progression
Selected publications
Schwartz GG, Tretli S, Klug MG, Robsahm TE. Women who develop ovarian cancer show an increase in serum calcium and a decrease in serum albumin. A longitudinal study in the Janus Serum Bank Cohort. Gynecol Oncol. 2020 Jul 25:S0090-8258(20)32381-7. doi: 10.1016/j.ygyno.2020.07.006.
Robsahm TE, Stenehjem JS, Berge LAM, Veierød MB. Prevalence of Indoor Tanning Among Teenagers in Norway Before and After Enforcement of Ban for Ages Under 18 Years. Acta Derm Venereol. 2020 Apr 29;100(8):adv00127. doi: 10.2340/00015555-3482.
Ghiasvand R, Robsahm TE, Green AC, Rueegg CS, Weiderpass E, Lund E, Veierød MB. Association of Phenotypic Characteristics and UV Radiation Exposure With Risk of Melanoma on Different Body Sites. JAMA Dermatol. 2019 Jan 1;155(1):39-49. doi: 10.1001/jamadermatol.2018.3964.
Hektoen HH, Robsahm TE, Andreassen BK, Stenehjem JS, Axcrona K, Mondul A, Gislefoss RE. Lifestyle associated factors and risk of urinary bladder cancer: A prospective cohort study from Norway.
Cancer Med. 2020 Jun;9(12):4420-4432. doi: 10.1002/cam4.3060.
Robsahm TE, Hestvik UE, Veierød MB, Fagerlie A, Nystad W, Engebretsen L, Tretli S. Cancer risk in Norwegian world class athletes. Cancer Causes Control. 2010 Oct;21(10):1711-9. doi: 10.1007/s10552-010-9600-z.
Robsahm TE, Tretli S, Torjesen PA, Babigumira R, Schwartz GG. Serum 25-hydroxyvitamin D levels predict cancer survival: a prospective cohort with measurements prior to and at the time of cancer diagnosis. Clin Epidemiol. 2019 Aug 8;11:695-705. doi: 10.2147/CLEP.S207230.
https://www.vg.no/forbruker/helse/i/VRlwJV/soerlendinger-mer-utsatt-for-hudkreft
https://www.nrk.no/norge/ny-studie_-d-vitamin-oker-sjansen-for-a-overleve-kreft-1.14680538
https://www.dagbladet.no/tema/supervitamin-bedrer-overlevelsen-ved-kreft/71554497
https://finansavisen.no/nyheter/livsstil/2016/06/mer-trening-gir-mindre-kreftrisiko
https://www.nettavisen.no/livsstil/trening-minsker-risiko-for-kreft-hos-menn/3423331877.html
