The bias criteria is based on biological variation within and between individuals. If the percentage difference in component level between fresh and long term stored samples does not exceed the allowed bias, one may report the difference as negligible.
The Janus biobank was not established for genetical studies, however a part of the samples contains restricted amount of DNA for SNP analyses. So far the quality and amount of DNA have not been documented, still the samples have been used in two genotype studies with a success rate up to 97.9 %.A microRNA study using the Janus material showed stable levels over time.